Plant Transcription Factor Database
Previous version: v3.0
Thellungiella parvula
ARF Family
Species TF ID Description
Tp1g17120ARF family protein
Tp1g17650ARF family protein
Tp1g26190ARF family protein
Tp2g04790ARF family protein
Tp2g25180ARF family protein
Tp4g04480ARF family protein
Tp4g11140ARF family protein
Tp4g16280ARF family protein
Tp4g28570ARF family protein
Tp5g01540ARF family protein
Tp5g20660ARF family protein
Tp5g33010ARF family protein
Tp6g08360ARF family protein
Tp6g09930ARF family protein
Tp6g22030ARF family protein
Tp6g23750ARF family protein
Tp7g05420ARF family protein
Tp7g21940ARF family protein
Tp7g27920ARF family protein
Tp7g27930ARF family protein
Tp_un0053_006ARF family protein
Tp_un0752_001ARF family protein
ARF Family Introduction

Auxin response factors (ARF) are transcription factors that regulate the expression of auxin response genes. ARFs bind with specificity to TGTCTC auxin response elements (AuxRE) in promoters of these genes and function in combination with Aux/IAA (auxin/indole acetic acid) repressors, which dimerize with ARF activators in an auxin-regulated manner.

Most ARFs consist of an amino-terminal DNA-binding domain (DBD), a middle region that functions as an activation domain (AD) or repression domain (RD), and a carboxy-terminal dimerization domain (CTD). The ARF DBD is classified as a plant-specific B3-type, but requires additional amino-terminal and carboxy-terminal amino acids for efficient in vitro binding to TGTCTC AuxREs.

The ARF ADs and RDs are located just carboxy-terminal to the DBDs and contain biased amino acid sequences. ARF ADs are enriched in glutamine along with serine and leucine residues, while ARF RDs are enriched in serine, proline, leucine and glycine residues.

Guilfoyle TJ, Hagen G.
Auxin response factors.
Curr Opin Plant Biol, 2007. 10(5): p. 453-60.
PMID: 17900969